Endocrine Abstracts

Thyroid cancers constitute 2% of all cancer cases most of which are differentiated. Tumor size, lymph node metastases and thyroglobulin levels (Tg) in the follow-up period are among the major factors responsible for recurrence. In this study, we aimed to review our series of differentiated thyroid cancers and establish the risks of recurrence.This study was carried out through a retrospective analysis of 393 differentiated thyroid cancer cases that were ...

Introduction: Metabolic syndrome (MetS) is a group of metabolic abnormalities where insulin resistance (IR) plays a major role. Previous studies have shown that thyroid volume and nodule prevalence were increased in patients with IR. The aim of our study is to evaluate MetS and its components in patients with benign and malignant nodular thyroid disease (NTD).Methods: A total of 800 patients (430 euthyroid benign and 370 euthyroid malignant NTD) followed...

The prevalance of incidentally discovered adrenal masses increased in last three decades. The major clinical concern is the risk of malignancy and hormone overproduction but most of them are non-fonctional and benign. Current practices in the management of adrenal incidentalomas reevaluated the follow-up suggestions considering low probability of the transformation of a benign and non-functional adrenal mass to a malignant or functional one. Therefore, in the present study we ...

Introduction: Feochromositoma is a rare neuroendocrine tumor derived from chrommaffin cells of adrenal medulla. The most characteristic clinical symptoms are headache, perspiration, palpitation, and paroxysismal hypertension. Childhood feochromositoma is generally genetic while it is mostly sporadic in adults. Here we report three feochromositoma cases in whom two had von Hippel Lindau syndrome (VHLs).Case 1: 10 years old girl with admitted with fever. H...

Background: Thyroid carcinomas are the most frequent endocrine malignancies of which more than nighty percent are differentiated thyroid carcinomas (DTC). It’s known that genetic variation plays 75% role in the development of papillary thyroid carcinoma (PTC).Material and methods: In a case control setting subjects between January 2005 and December 2015 were evaluated for inclusion in the study. We aimed to compare the genotype frequency distributio...

Sarcoidosis is a multisystem granulomatous disease of unknown cause. The prevalence of neurosarcoidosis is about 5–15%. Hypothalamo-pituitary sarcoidosis is even rarer (<1% of cases evaluated for sellar and stalk lesions).Case Report: A 33-year-old man presented to urology department with erectile dysfunction which started six months ago. Hormonal evaluation revealed gonadotropin deficiency and hyperprolactinemia (Total testosterone: 30.5 ng/dl,...

Introduction: Previous reports have shown that subjects with insulin resistance have increased thyroid volume and nodule prevalence. We investigated the effects of metformin on thyroid volume and nodule size.Methods: This prospective data were gathered on newly diagnosed subjects with insulin resistance (n=100, 68 female, 32 male) between August 2008 and May 2010. Measurements of thyroid hormones and thyroid ultrasonography was performed in all ...

Introduction: There is accumulating evidence on the favourable effects of some statins on bone and mineral metabolism. Although some studies have reported drop of serum 25-hydroxyvitamin D levels in subjects receiving statin therapy, comparative studies evaluating various statins in prospective randomized design is lacking. Our purpose is to compare the effects of variable doses of rosuvastatin and atorvastatin on serum 25-hydoxyvitamin D levels adjusted for seasons.<p cla...

Objective: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities with insulin resistance (IR) as a major characteristic. It has been recently questioned that MetS and its related components are associated with functional and morphological alterations of thyroid gland. Aim of our study is to examine thyroid volume and nodule prevalence in patients with MetS in a mild-to-moderate iodine deficient area.Design: Two hundred and seventy-eight p...

Objective: Efficacy of eutectic mixture of local anesthetics (EMLA) cream and the needle-free injection of local anesthesia for reducing the pain associated with fine-needle aspiration biopsy (FNAB) of thyroid nodules was previously reported. However, direct comparison of the analgesic efficacy for both methods has not been established yet. The aim of this study was to compare the analgesic efficacy of EMLA cream and needle-free injection of lidocaine for FNAB-associated pain....